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Lymphoma - Overview

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What Is Lymphoma?

Lymphoma Overview Section 2

Lymphoma is a cancer that begins in your lymphatic system. This system is key to fighting infections and includes parts like your lymph nodes, spleen, thymus gland, and bone marrow.


Lymphoma primarily targets lymphocytes, a type of white blood cell in your immune system. These cells in your lymph nodes and other lymphatic system areas can be affected. Being a blood cancer, lymphoma has the potential to influence various parts of your body

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Worried about lymphoma? Or need guidance during your treatment? We're here to help. Contact our experienced haematologist-oncologist in London for dedicated support and expert care.

The Four Stages Of Lymphoma

Both Hodgkin and non-Hodgkin lymphoma have similar staging systems, numbered 1 to 4 or I to IV. Sometimes, additional letters are used.

Staging is based on the lymphoma's location in relation to the diaphragm.

Lymphoma in One Node Group


This is when lymphoma is present in only one group of lymph nodes.

Stage 1E


The lymphoma started in a single organ outside the lymphatic system (like the liver) and is only in that organ.

Lymphoma in Multiple Node Groups

Here, lymphoma appears in two or more groups of lymph nodes, but all on the same side of the diaphragm.

Stage 2E

The lymphoma began in an organ (not in the lymphatic system) and has spread to one or more lymph node groups on the same side of the diaphragm.

Lymphoma on Both Sides of the Diaphragm

Lymph nodes containing lymphoma are found above and below the diaphragm.


Most Advanced Stage

Lymphoma that has spread from the lymph nodes to at least one body organ outside the lymphatic system (like the lungs or liver).

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Types Of Lymphoma

Non-Hodgkin Lymphoma

Non-Hodgkin lymphoma is an umbrella term. It includes a lot of different subtypes, like Diffuse large B-cell and follicular lymphoma. Each one is unique and needs its own treatment plan. With such a variety, doctors focus on what works best for each type and individual.

Hodgkin Lymphoma

Hodgkin lymphoma (also known as Hodgkin disease) has a special marker: the Reed-Sternberg cell. It behaves a bit different and needs its own treatment approach. This lymphoma tends to move from one lymph node to the next in order, not all over the place. It's often one of the easiest types of cancer to treat, especially if diagnosed and treated early.

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