Depression - Symptoms & Causes

Depression is a common but serious mood disorder that negatively affects how you feel, think, and act. It can cause feelings of sadness, hopelessness, and a loss of interest in activities you once enjoyed. Depression can significantly impact your daily life, relationships, and work. However, it's important to know that depression is treatable. Here at LIPS, our team of specialists is dedicated to providing effective treatment options to help you manage depression and regain control of your well-being.

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Depression Symptoms

The signs of depression vary from person to person. Common symptoms include the following:

Persistent Sadness or Emptiness

This unrelenting feeling is often the hallmark symptom. In children, this may show up as heightened irritability.

Loss of Interest

Once-loved activities lose their spark, leading to withdrawal from hobbies, social life, or daily routines.


Minor triggers can lead to disproportionate anger or frustration in individuals with depression.

Appetite and Weight Changes

Significant shifts in eating habits, leading to weight gain or loss, are common indicators.

Sleep Disturbances

 Insomnia or excessive sleep are both red flags for depression.

Fatigue and Low Energy

Continuous tiredness despite adequate rest is another common symptom.

Concentration Difficulties

Focusing, making decisions, or remembering things can become challenging for those with depression.

Physical Symptoms

Unexplained aches, pains, or sexual dysfunction can be linked to depression.

Thoughts of Self-Harm or Suicide

These serious warning signs require immediate professional attention.


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Causes of Depression

Depression arises from a complex interplay of factors rather than a single cause. Understanding these contributing elements can provide insight into the condition.

Below are some key factors that may lead to depression:

Neurotransmitter Imbalance

An imbalance in brain chemicals — particularly serotonin and dopamine, which regulate mood — can contribute to the onset of depression.

Genetic Predisposition

Having a close relative with depression may increase your risk, though it's not a definitive predictor. Depression can occur without a family history.

Life Stressors

Major life events can act as catalysts for depression, such as loss, divorce, or severe stress.

Persistent Medical Issues

Long-term health conditions, like chronic pain or ongoing medical challenges, are often linked to the development of depression.

Medication and Substance Influence

Some prescribed medications might have depression as a side effect. Additionally, the use of substances like alcohol can trigger or exacerbate depression.


If you are experiencing signs of depression or know someone who might be, reaching out for professional help is a key step towards recovery. Our clinic in London offers dedicated treatment and support for depression, tailored to individual needs.

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Schedule a Video Consultation or a Face-to-Face appointment at your convenience by using our online booking system.


Schedule a Video Consultation or a Face-to-Face appointment at your convenience by using our online booking system.

Your dedicated Specialist Doctor will provide you with personalized treatment, tailoring it to your specific needs, and may include necessary medication.


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Registered Office Address

London International Patient Services Limited.

Solar House,

282 Chase Road, London,

United Kingdom, N14 6NZ

Company number: 10111760.

Registered in England and Wales.

LIPS is the UK’s largest multispecialty

private group of leading NHS teaching hospital


Based in London, United Kingdom

Mon – Fri: 8 AM – 7 PM

Sat: 8 AM – 4 PM

Sun: Closed